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1

Follow the ATP: Tumor Energy Production: A Perspective

Oronsky, Bryan, Oronsky, Neil, Fanger, Gary, Parker, Christopher, Caroen, Scott, Lybeck, Michelle, Scicinski, Jan

Journal:

Anti-Cancer Agents in Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 786 KB

english, 2014

2

Six Degrees of Separation: The Oxygen Effect in the Development of Radiosensitizers

Oronsky, Bryan T., Knox, Susan J., Scicinski, Jan

Journal:

Translational Oncology

Year:

2011

Language:

english

File:

PDF, 290 KB

english, 2011

3

“No patient left behind”: an alternative to “the War on Cancer” metaphor

Oronsky, Bryan T., Carter, Corey A., Oronsky, Arnold L., Salacz, Michael E., Reid, Tony

Journal:

Medical Oncology

Year:

2016

Language:

english

File:

PDF, 308 KB

english, 2016

4

Is Nitric Oxide (NO) the Last Word in Radiosensitization? A Review

Oronsky, Bryan T., Knox, Susan J., Scicinski, Jan J.

Journal:

Translational Oncology

Year:

2012

Language:

english

File:

PDF, 188 KB

english, 2012

5

RRx-001: a systemically non-toxic M2-to-M1 macrophage stimulating and prosensitizing agent in Phase II clinical trials

Oronsky, Bryan, Paulmurugan, Ramasamy, Foygel, Kira, Scicinski, Jan, Knox, Susan J., Peehl, Donna, Zhao, Hongjuan, Ning, Shoucheng, Cabrales, Pedro, Summers, Thomas A., Reid, Tony R., Fitch, William L

Journal:

Expert Opinion on Investigational Drugs

Year:

2017

Language:

english

File:

PDF, 1.15 MB

english, 2017

6

Going viral: a review of replication-selective oncolytic adenoviruses

Larson, Christopher, Oronsky, Bryan, Scicinski, Jan, Fanger, Gary R., Stirn, Meaghan, Oronsky, Arnold, Reid, Tony R.

Journal:

Year:

2015

Language:

english

File:

PDF, 974 KB

english, 2015

7

TGF-Beta: A master immune regulator

Larson, Christopher, Oronsky, Bryan, Carter, Corey A., Oronsky, Arnold, Knox, Susan J., Sher, David, Reid, Tony R

Journal:

Expert Opinion on Therapeutic Targets

Year:

2020

Language:

english

File:

PDF, 1.20 MB

english, 2020

8

Just eat it: A review of CD47 and SIRP-Î± antagonism

Oronsky, Bryan, Carter, Corey, Reid, Tony, Brinkhaus, Franck, Knox, Susan J.

Journal:

Seminars in Oncology

Year:

2020

File:

PDF, 1.08 MB

2020

9

Studies on the effect of CL 306,293, a substituted quinoline car☐ylic acid, on the clinical disease induced in mice with LP-BM5 virus

Jeffery W. Scott, Susan Quinn DeJoy, Robert Jeyaseelan Sr., Dennis W. Powell, Carmen Raventos-Suarez, Bryan O'Hara, Michael M. Wick, Arnold L. Oronsky, S.S. Kerwar

Journal:

Antiviral Research

Year:

1993

Language:

english

File:

PDF, 629 KB

english, 1993

10

Novel nitric oxide generating compound glycidyl nitrate enhances the therapeutic efficacy of chemotherapy and radiotherapy

Ning, Shoucheng, Bednarski, Mark, Oronsky, Bryan, Scicinski, Jan, Knox, Susan J.

Journal:

Biochemical and Biophysical Research Communications

Year:

2014

Language:

english

File:

PDF, 429 KB

english, 2014

11

Meeting Announcements

Ning, Shoucheng, Bednarski, Mark, Oronsky, Bryan, Scicinski, Jan, Knox, Susan J.

Journal:

Journal of Renal Nutrition

Year:

2001

Language:

english

File:

PDF, 26 KB

english, 2001

12

Beyond Antiangiogenesis: Vascular Modulation as an Anticancer Therapy—A Review

Oronsky, Bryan T., Scicinski, Jan J., Reid, Tony, Knox, Susan

Journal:

Translational Oncology

Year:

2012

Language:

english

File:

PDF, 260 KB

english, 2012

13

The Implications of Hyponitroxia in Cancer

Oronsky, Bryan, Fanger, Gary R., Oronsky, Neil, Knox, Susan, Scicinski, Jan

Journal:

Translational Oncology

Year:

2014

Language:

english

File:

PDF, 590 KB

english, 2014

14

Development of methods for the bioanalysis of RRx-001 and metabolites

Scicinski, Jan, Oronsky, Bryan, Cooper, Vance, Taylor, Michael, Alexander, Mike, Hadar, Rebecca, Cosford, Rebecca, Fleischmann, Thomas, Fitch, William L

Journal:

Year:

2014

Language:

english

File:

PDF, 879 KB

english, 2014

15

The Scarlet Letter of Alkylation: A Mini Review of Selective Alkylating Agents

Oronsky, Bryan T., Reid, Tony, Knox, Susan J., Scicinski, Jan J.

Journal:

Translational Oncology

Year:

2012

Language:

english

File:

PDF, 131 KB

english, 2012

16

Rewriting the Epigenetic Code for Tumor Resensitization: A Review

Oronsky, Bryan, Oronsky, Neil, Scicinski, Jan, Fanger, Gary, Lybeck, Michelle, Reid, Tony

Journal:

Translational Oncology

Year:

2014

Language:

english

File:

PDF, 355 KB

english, 2014

17

The War on Cancer: A Military Perspective

Oronsky, Bryan, Carter, Corey A., Mackie, Vernon, Scicinski, Jan, Oronsky, Arnold, Oronsky, Neil, Caroen, Scott, Parker, Christopher, Lybeck, Michelle, Reid, Tony

Journal:

Frontiers in Oncology

Year:

2015

Language:

english

File:

PDF, 692 KB

english, 2015

18

Impact of hemoglobin nitrite to nitric oxide reductase on blood transfusion for resuscitation from hemorrhagic shock

Cabrales, Pedro, Brouse, Chad, Ortiz, Daniel, Su, Yan, Oronsky, Bryan, Scicinski, Jan

Journal:

Asian Journal of Transfusion Science

Year:

2015

Language:

english

File:

PDF, 1.22 MB

english, 2015

19

NO to cancer: The complex and multifaceted role of nitric oxide and the epigenetic nitric oxide donor, RRx-001

Scicinski, Jan, Oronsky, Bryan, Ning, Shoucheng, Knox, Susan, Peehl, Donna, Kim, Michelle M., Langecker, Peter, Fanger, Gary

Journal:

Year:

2015

Language:

english

File:

PDF, 3.48 MB

english, 2015

20

Safety and activity of RRx-001 in patients with advanced cancer: a first-in-human, open-label, dose-escalation phase 1 study

Reid, Tony, Oronsky, Bryan, Scicinski, Jan, Scribner, Curt L, Knox, Susan J, Ning, Shoucheng, Peehl, Donna M, Korn, Ron, Stirn, Meaghan, Carter, Corey A, Oronsky, Arnold, Taylor, Michael J, Fitch, Wil

Journal:

The Lancet Oncology

Year:

2015

Language:

english

File:

PDF, 553 KB

english, 2015

21

Concurrent whole brain radiotherapy and RRx-001 for melanoma brain metastases

Kim, Michelle M., Parmar, Hemant, Cao, Yue, Knox, Susan J., Oronsky, Bryan, Scicinski, Jan, Lawrence, Theodore S., Lao, Christopher D.

Journal:

Year:

2016

Language:

english

File:

PDF, 189 KB

english, 2016

22

Partial response to carboplatin in an RRx-001 pretreated patient with EGFR-inhibitor-resistance and T790M-negative NSCLC

Carter, Corey A., Oronsky, Bryan, Caroen, Scott, Scicinski, Jan, Cabrales, Pedro, Degesys, Aiste, Brzezniak, Christina

Journal:

Respiratory Medicine Case Reports

Year:

2016

Language:

english

File:

PDF, 952 KB

english, 2016

23

The Development Of RRx-001, A Novel Nitric-Oxide-Mediated Epigenetically Active Anticancer Agent

Scicinski, Jan, Fisher, George, Carter, Corey, Cho-Phan, Cheryl, Kunz, Pamela, Ning, Shoucheng, Knox, Susan, Oronsky, Bryan, Caroen, Scott, Parker, Christopher, Fanger, Gary, Reid, Tony

Journal:

Year:

2015

Language:

english

File:

PDF, 49 KB

english, 2015

24

Confirmatory Trials in the Evaluation of Anticancer Medicinal Products in Man—PFS2: A Measure of Therapeutic Action-At-A-Distance

Oronsky, Bryan, Carter, Corey A., Reid, Tony R., Scicinski, Jan, Oronsky, Arnold, Lybeck, Michelle, Caroen, Scott, Stirn, Meaghan, Oronsky, Neil, Langecker, Peter

Journal:

Year:

2015

Language:

english

File:

PDF, 770 KB

english, 2015

25

From METS to malaria: RRx-001, a multi-faceted anticancer agent with activity in cerebral malaria

Yalcin, Ozlem, Oronsky, Bryan, Carvalho, Leonardo, Kuypers, Frans, Scicinski, Jan, Cabrales, Pedro

Journal:

Malaria Journal

Year:

2015

Language:

english

File:

PDF, 3.51 MB

english, 2015

26

RRx-001, an epigenetic-based radio- and chemosensitizer, has vascular normalizing effects on SCCVII and U87 tumors

Oronsky, Bryan, Scicinski, Jan, Cabrales, Pedro, Minchinton, Andrew

Journal:

Clinical Epigenetics

Year:

2016

Language:

english

File:

PDF, 2.97 MB

english, 2016

27

RRx-001, A novel dinitroazetidine radiosensitizer

Oronsky, Bryan, Scicinski, Jan, Ning, Shoucheng, Peehl, Donna, Oronsky, Arnold, Cabrales, Pedro, Bednarski, Mark, Knox, Susan

Journal:

Investigational New Drugs

Year:

2016

Language:

english

File:

PDF, 1.13 MB

english, 2016

28

Targeting tumor hypoxia with the epigenetic anticancer agent, RRx-001: a superagonist of nitric oxide generation

Fens, Marcel H., Cabrales, Pedro, Scicinski, Jan, Larkin, Sandra K., Suh, Jung H., Kuypers, Frans A., Oronsky, Neil, Lybeck, Michelle, Oronsky, Arnold, Oronsky, Bryan

Journal:

Medical Oncology

Year:

2016

Language:

english

File:

PDF, 1.29 MB

english, 2016

29

Immune Reactivity and Pseudoprogression or Tumor Flare in a Serially Biopsied Neuroendocrine Patient Treated with the Epigenetic Agent RRx-001

Carter, Corey A., Schmitz, Bruno, Peterson, P. Gabriel, Quinn, Mary, Degesys, Aiste, Jenkins, John, Oronsky, Bryan, Scicinski, Jan, Caroen, Scott, Reid, Tony R., Cabrales, Pedro, Brzezniak, Christina

Journal:

Case Reports in Oncology

Year:

2016

Language:

english

File:

PDF, 823 KB

english, 2016

30

A look inside the mechanistic black box: Are red blood cells the critical effectors of RRx-001 cytotoxicity?

Cabrales, Pedro, Scicinski, Jan, Reid, Tony, Kuypers, Frans, Larkin, Sandra, Fens, Marcel, Oronsky, Arnold, Oronsky, Bryan

Journal:

Medical Oncology

Year:

2016

Language:

english

File:

PDF, 1.01 MB

english, 2016

31

The immunomodulatory anticancer agent, RRx-001, induces an interferon response through epigenetic induction of viral mimicry

Zhao, Hongjuan, Ning, Shoucheng, Nolley, Rosalie, Scicinski, Jan, Oronsky, Bryan, Knox, Susan J., Peehl, Donna M.

Journal:

Clinical Epigenetics

Year:

2017

Language:

english

File:

PDF, 2.61 MB

english, 2017

32

P2.06-031 QUADRUPLE THREAT: A Pilot Phase 2 Study of RRx-001 in Advanced Lung Cancer Prior to Re-Administration of Platinum Doublets

Brzezniak, Christina, Quinn, Mary, Zeman, Karen, Oronsky, Bryan, Scicinski, Jan, Caroen, Scott, Abrouk, Nacer, Degesys, Aiste, Schmitz, Bruno, Peterson, Paul, Roswarski, Joe, Trepel, Jane, Lee, Min-Ju

Journal:

Journal of Thoracic Oncology

Year:

2017

Language:

english

File:

PDF, 203 KB

english, 2017

33

Conversion of Platinum-Etoposide-Resistant to Sensitive SCLC after Treatment with the Epi-Immunotherapeutic RRx-001: A Case Report

Brzezniak, Christina, Oronsky, Bryan, Scicinski, Jan, Caroen, Scott, Cabrales, Pedro, Dean Abrouk, Nacer, Kim, Michelle M., Brown, James F., Reid, Tony R., Larson, Christopher, Oronsky, Arnold, Day, R

Journal:

Oncology Research and Treatment

Year:

2016

Language:

english

File:

PDF, 521 KB

english, 2016

34

RRx-001 protects against cisplatin-induced toxicities

Oronsky, Bryan, Reid, Tony R., Larson, Christopher, Carter, Corey A., Brzezniak, Christina E., Oronsky, Arnold, Cabrales, Pedro

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

2017

Language:

english

File:

PDF, 987 KB

english, 2017

35

A brief review of the management of platinum-resistant–platinum-refractory ovarian cancer

Oronsky, Bryan, Ray, Carolyn M., Spira, Alexander I., Trepel, Jane B., Carter, Corey A., Cottrill, Hope M.

Journal:

Medical Oncology

Year:

2017

Language:

english

File:

PDF, 518 KB

english, 2017

36

Partial Response to Platinum Doublets in Refractory EGFR-Positive Non-Small Cell Lung Cancer Patients after RRx-001: Evidence of Episensitization

Carter, Corey A., Oronsky, Bryan T., Caroen, Scott Z., Scicinski, Jan J., Cabrales, Pedro, Reid, Tony, Degesys, Aiste, Jenkins, John, Brzezniak, Christina

Journal:

Case Reports in Oncology

Year:

2016

Language:

english

File:

PDF, 908 KB

english, 2016

37

The macrophage stimulating anti-cancer agent, RRx-001, protects against ischemia-reperfusion injury

Cabrales, Pedro, Caroen, Scott, Oronsky, Arnold, Carter, Corey, Trepel, Jane, Summers, Thomas, Reid, Tony, Oronsky, Neil, Lybeck, Michelle, Oronsky, Bryan

Journal:

Expert Review of Hematology

Year:

2017

Language:

english

File:

PDF, 2.40 MB

english, 2017

38

Electrolyte disorders with platinum-based chemotherapy: mechanisms, manifestations and management

Oronsky, Bryan, Caroen, Scott, Oronsky, Arnold, Dobalian, Vaughn E., Oronsky, Neil, Lybeck, Michelle, Reid, Tony R., Carter, Corey A.

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2017

Language:

english

File:

PDF, 2.35 MB

english, 2017

39

No Patient Left Behind: The Promise of Immune Priming With Epigenetic Agents

Carter, Corey A., Oronsky, Bryan T., Roswarski, Joseph, Oronsky, Arnold L., Oronsky, Neil, Scicinski, Jan, Lybeck, Harry, Kim, Michelle M., Lybeck, Michelle, Reid, Tony R.

Journal:

Year:

2017

Language:

english

File:

PDF, 3.59 MB

english, 2017

40

What's New in SCLC? A Review

Oronsky, Bryan, Reid, Tony R., Oronsky, Arnold, Carter, Corey A.

Journal:

Year:

2017

Language:

english

File:

PDF, 408 KB

english, 2017

41

A Complete Metabolic Response of Metastatic Castration-resistant Neuroendocrine Carcinoma of the Prostate After Treatment with RRx-001 and Reintroduced Platinum Doublets

Brzezniak, Christina, Oronsky, Bryan, Aggarwal, Rahul

Journal:

European Urology

Year:

2017

Language:

english

File:

PDF, 589 KB

english, 2017

42

RRx-001 Priming of PD-1 Inhibition in the Treatment of Small Cell Carcinoma of the Vagina: A Rare Gynecological Tumor

Brzezniak, Christina, Oronsky, Bryan, Trepel, Jane, Summers Jr., Thomas A., Cabrales, Pedro, Lee, Min-Jung, Day, Regina, Jha, Saheli, Caroen, Scott, Zeman, Karen, Ferry, Lindsey, Harmer, Cindy, Oronsk

Journal:

Case Reports in Oncology

Year:

2017

Language:

english

File:

PDF, 533 KB

english, 2017

43

Nothing But NET: A Review of Neuroendocrine Tumors and Carcinomas

Oronsky, Bryan, Ma, Patrick C., Morgensztern, Daniel, Carter, Corey A.

Journal:

Year:

2017

Language:

english

File:

PDF, 906 KB

english, 2017

44

A Partial Response to Reintroduced Chemotherapy in a Resistant Small Cell Lung Cancer Patient after Priming with RRx-001

Oronsky, Bryan, Caroen, Scott, Zeman, Karen, Quinn, Mary, Brzezniak, Christina, Scicinski, Jan, Cabrales, Pedro, Reid, Tony R., Trepel, Jane B., Abrouk, Nacer D., Larson, Christopher, Oronsky, Arnold,

Journal:

Clinical Medicine Insights Oncology

Year:

2016

Language:

english

File:

PDF, 922 KB

english, 2016

45

Dysphonia after Bevacizumab Rechallenge: A Case Report

Carter, Corey A., Caroen, Scott Z., Oronsky, Arnold L., Oronsky, Bryan T.

Journal:

Case Reports in Oncology

Year:

2015

Language:

english

File:

PDF, 502 KB

english, 2015

46

Flushing Out Carcinoid Syndrome: Beneficial Effect of the Anticancer Epigenetic Agent RRx-001 in a Patient with a Treatment-Refractory Neuroendocrine Tumor

Carter, Corey A., Degesys, Aiste, Oronsky, Bryan, Scicinski, Jan, Caroen, Scott Z., Oronsky, Arnold L., Reid, Tony, Cabrales, Pedro, Roswarski, Joe

Journal:

Case Reports in Oncology

Year:

2015

Language:

english

File:

PDF, 863 KB

english, 2015

47

Navigating the “No Man's Land” of TKI-Failed EGFR-Mutated Non–Small Cell Lung Cancer (NSCLC): A Review

Oronsky, Bryan, Ma, Patrick, Reid, Tony R., Cabrales, Pedro, Lybeck, Michelle, Oronsky, Arnold, Oronsky, Neil, Carter, Corey A.

Journal:

Year:

2018

Language:

english

File:

PDF, 755 KB

english, 2018

48

Superior Vena Cava Syndrome in a Patient with Small-Cell Lung Cancer: A Case Report

Brzezniak, Christina, Oronsky, Bryan, Carter, Corey A., Thilagar, Bennett, Caroen, Scott, Zeman, Karen

Journal:

Case Reports in Oncology

Year:

2017

Language:

english

File:

PDF, 765 KB

english, 2017

49

Pulmonary Tumor Thrombotic Microangiopathy: A New Paraneoplastic Syndrome

Carter, Corey A., Scicinski, Jan J., Lybeck, Harry E., Oronsky, Bryan T.

Journal:

Case Reports in Oncology

Year:

2016

Language:

english

File:

PDF, 459 KB

english, 2016

50

A note on improved statistical approaches to account for pseudoprogression

Abrouk, Nacer, Oronsky, Bryan, Caroen, Scott, Ning, Shoucheng, Knox, Susan, Peehl, Donna

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2018

Language:

english

File:

PDF, 1.54 MB

english, 2018

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